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Beaks, Bills and Climate
By SINDYA N. BHANOO, The New York Times, June 28, 2010

In the 1800s, an American zoologist named Joel Allen posited that animals in cold climates evolved to have shorter appendages (limbs, ears, and tails) than those in hot climates, in order to minimize surface area and thereby minimize heat loss. The theory, known as Allen’s rule, has long appeared in biology books, but scientific evidence for it has remained weak.

Now a study comparing bird bills provides the most substantial evidence yet in support of Allen’s rule.

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Effort Uses Dogs’ DNA to Track Their Abusers
By MALCOLM GAY, The New York Times, June 25, 2010

ST. LOUIS — Scientists and animal rights advocates have enlisted DNA evidence to do for man’s best friend what the judicial system has long done for human crime victims. They have created the country’s first dog-fighting DNA database, which they say will help criminal investigators piece together an abused animal’s history by establishing ties among breeders, owners, pit operators and the animals themselves.

Called the Canine Codis, or Combined DNA Index System, the database is similar to the Federal Bureau of Investigation’s digital archive containing the DNA profiles of criminal offenders. Scientists say that by swabbing the inner cheek of a dog, they will be able to determine whether the animal comes from one of several known dog-fighting bloodlines.

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Antibiotics in Animals Need Limits, F.D.A. Says
By GARDINER HARRIS, The New York Times, June 28, 2010

WASHINGTON — Federal food regulators took a tentative step Monday toward banning a common use of penicillin and tetracycline in the water and feed given cattle, chickens and pigs in hopes of slowing the growing scourge of killer bacteria.

But the Food and Drug Administration has tried without success for more than three decades to ban such uses. In the past, Congress has stepped in at the urging of agricultural interests and stopped the agency from acting.

In the battle between public health and agriculture, the guys with the cowboy hats generally win.

The F.D.A. released a policy document stating that agricultural uses of antibiotics should be limited to assuring animal health, and that veterinarians should be involved in the drugs’ uses.

While doing nothing to change the present oversight of antibiotics, the document is the first signal in years that the agency intends to rejoin the battle to crack down on agricultural uses of antibiotics that many infectious disease experts oppose.

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Exercise: Bicycling to Keep Off Extra Pounds
By RONI CARYN RABIN, The New York Times, June 28, 2010

Bicycling for exercise may help women control their weight during their 30s and 40s, a new study says.

Brisk walking has the same effect for slim, overweight and obese women, researchers found, but slow walking does not.

The findings are based on the second Harvard Nurses’ Health Study, which is tracking 116,608 female nurses who periodically fill out questionnaires about their health, weight, diet and behavior. The new analysis, published in the June 28 issue of Archives of Internal Medicine, looked at weight change and behavior from 1989 (when the nurses were 25 to 42 years old) to 2005; to isolate the effects of exercise, the researchers controlled for other obesity risk factors.

They found that women who increased physical activities like brisk walking and bicycling by 30 minutes a day during the 16-year period maintained their weight and even lost a few pounds, but those whose exercise was slow walking did not lose any weight.

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Childhood: Combination Vaccine and Seizure Risk
By RONI CARYN RABIN, The New York Times, June 28, 2010

Toddlers who get a vaccine that combines the measles-mumps-rubella and chickenpox immunizations are at twice the usual risk for fevers that lead to convulsions, a new study reports.

The risk for a so-called febrile seizure after any measles vaccination is less than 1 seizure per 1,000 vaccinations; but among children who received the combined vaccine, there is 1 additional seizure for every 2,300 vaccinated, said Dr. Nicola Klein, the study’s lead investigator and director of the Kaiser Permanente Vaccine Study Center.

The reactions, which occur a week to 10 days after vaccination, are not life-threatening and usually resolve on their own. The fever-related convulsions can be frightening, but they are brief and not linked to any long-term complications or seizure disorders.

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Rethinking the Way We Rank Medical Schools
By PAULINE W. CHEN, M.D., The New York Times, June 17, 2010

During my internship, the first year after graduating from medical school, I took care of a middle-aged woman who began our first conversation with a question that patients still ask me today.

“So doctor,” she said as I pulled my stethoscope out to listen to her heart, “where did you go to medical school?”

In a social context, I might have considered her question to be polite chatter, a filler during an awkward quiet moment. But on that particular afternoon her words felt more like a dart lobbed at what I had presumed to be a budding and promising patient-doctor relationship.

Trust from this patient, I remember thinking, is not going to depend on my bedside manner or clinical judgment but my medical school.

But even before I had placed my stethoscope bell against my patient’s chest, I realized that I, too, had been culpable of submitting doctors to the same line of questioning. Although I might have satisfied my curiosity more surreptitiously — searching on the Internet, scanning hospital directories, inconspicuously craning my neck to discern Latinized school names on diplomas — I was just as eager as my patient to learn about the medical schools my doctors had attended.

Once I had the information, I would do what my patient did that afternoon: I would mentally find its place within the medical school hierarchy in my mind. Like some existential fast forward button, the right answer to this question could raise the trust in any patient-doctor relationship to a whole new level without a second thought, because by virtue of having graduated from a “good” school, that doctor had the ability to address the most pressing needs of all of his or her patients.

The thought process was easy — good school, good doctor; bad school, bad doctor.

Maybe.

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Paternal Bonds, Special and Strange
By NATALIE ANGIER, The New York Times, June 14, 2010

Not long ago, Julia Fischer of the German Primate Center in Göttingen was amused to witness two of her distinguished male colleagues preening about a topic very different from the standard academic peacock points — papers published, grants secured, competitors made to look foolish.

“One of them said proudly, ‘I have three children,’ ” Dr. Fischer recalled. “The other one replied, ‘Well, I have four children.’

“Some men might talk about their Porsches,” she added. “These men were boasting about their number of children.” And while Dr. Fischer is reluctant to draw facile comparisons between humans and other primates, she couldn’t help thinking of her male Barbary macaques, for whom no display carries higher status, or is more likely to impress the other guys, than to strut around the neighborhood with an infant monkey in tow.

Reporting in the current issue of the journal Animal Behaviour, Dr. Fischer and her co-workers describe how male Barbary macaques use infants as “costly social tools” for the express purpose of bonding with other males and strengthening their social clout. Want to befriend the local potentate? Bring a baby. Need to reinforce an existing male-male alliance, or repair a frayed one? Don’t forget the baby.

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Are Killer Viruses, Rendered in Glass, Also Things of Beauty?
By DONALD G. McNEIL Jr., The New York Times, June 14, 2010

In a gallery in Manhattan’s meatpacking district, balanced delicately on mirrored surfaces and quivering slightly with each passing truck, is a lineup of history’s greatest killers: smallpox, influenza, H.I.V.

They are all beautifully rendered in blown glass, their shining, spiky capsids (you have to wonder how they get the Windex into those delicate crevices) encasing their destructive RNA or DNA cores, which are rendered as spiraling dots of milky glass. They are beautiful hand grenades, the illusion heightened by their precarious perches over a hard floor.

Medical journals have cooed over them, and a rendition of the AIDS virus by the artist, Luke Jerram, is in the collection of the Wellcome Trust, Britain’s equivalent of the Bill and Melinda Gates Foundation.

But as someone covering infectious disease, I found myself offended: I’ve watched people dying of these things now rendered as $10,000 paperweights. There’s something unseemly about celebrating the beauty in something that does such ugly things — in a way that I don’t feel when Steuben does it to a snail.

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British Medical Council Bars Doctor Who Linked Vaccine With Autism
By JOHN F. BURNS, The New York Times, May 24, 2010

LONDON — A doctor whose research and public statements caused widespread alarm that a common childhood vaccine could cause autism was banned on Monday from practicing medicine in his native Britain for ethical lapses, including conducting invasive medical procedures on children that they did not need.

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Tracking the Ancestry of Corn Back 9,000 Years
By SEAN B. CARROLL, The New York Times, May 24, 2010

It is now growing season across the Corn Belt of the United States. Seeds that have just been sown will, with the right mixture of sunshine and rain, be knee-high plants by the Fourth of July and tall stalks with ears ripe for picking by late August.

Corn is much more than great summer picnic food, however. Civilization owes much to this plant, and to the early people who first cultivated it.

For most of human history, our ancestors relied entirely on hunting animals and gathering seeds, fruits, nuts, tubers and other plant parts from the wild for food. It was only about 10,000 years ago that humans in many parts of the world began raising livestock and growing food through deliberate planting. These advances provided more reliable sources of food and allowed for larger, more permanent settlements. Native Americans alone domesticated nine of the most important food crops in the world, including corn, more properly called maize (Zea mays), which now provides about 21 percent of human nutrition across the globe.

But despite its abundance and importance, the biological origin of maize has been a long-running mystery. The bright yellow, mouth-watering treat we know so well does not grow in the wild anywhere on the planet, so its ancestry was not at all obvious. Recently, however, the combined detective work of botanists, geneticists and archeologists has been able to identify the wild ancestor of maize, to pinpoint where the plant originated, and to determine when early people were cultivating it and using it in their diets.

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Male Antelopes Scare Partners Into Sex
By SINDYA N. BHANOO, The New York Times, May 24, 2010

This is a story about deception and sex in the wild plains of Kenya.

Antelope deception, that is, for the purposes of sex.

During mating season, a male topi antelope will try to keep females in heat from leaving his territory by pretending that a predator might be in the area, according to a study that will appear in the July issue of The American Naturalist.

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Tropical Diseases: Outbreak of Dengue Fever Is Reported in Florida, Health Officials Say
By DONALD G. McNEIL Jr., The New York Times, May 24, 2010

Dengue fever, a growing scourge in the tropics, has established itself in a popular American tourist destination, federal health officials reported last week.

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The Right Way to Warm Up Is (Your Answer Here)
By GINA KOLATA, The New York Times, May 17, 2010

At the Boston Marathon last month, my running partner, Jen Davis, said things were pretty much the same as the 10 other times she has run this race. Most runners stood around waiting for the race to start. Some did strides — short bursts of speed — or ran briefly at close to their race pace. There was a lot of stretching, too, and applications of heat rubs like Bengay and jumping up and down to stay warm.

My son, Stefan Kolata, was with the elite men this year in Boston and warmed up with them in their own special pre-race area. Those runners had a very different routine, he says. They spent about 15 minutes doing sort of a slow shuffle. There they were, a long line of elites, going around and around the warm-up area, barely lifting their legs.

Then, some went to a parking lot and did dynamic stretching — high knees, backward running, sideways running. Others vanished from the outdoor warm-up area, emerging again when the race was about to begin.

When it was all over, the men’s winner finished in 2:05:52, an average pace of 4 minutes 48 seconds per mile. Even the 10th-place finisher had a time of 2:10:33, or 4:59 a mile. So maybe these fast men know a secret about warm-ups.

Or maybe not.

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Creatures of Cambrian May Have Lived On
By JOHN NOBLE WILFORD, The New York Times, May 17, 2010

Ever since their discovery in 1909, the spectacular Burgess Shale outcrops in the Canadian Rockies have presented scientists with a cornucopia of evidence for the “explosion” of complex, multicellular life beginning some 550 million years ago.

The fossils, all new to science, were at first seen as little more than amazing curiosities from a time when life, except for bacteria and algae, was confined to the sea — and what is now Canada was just south of the Equator. In the last half century, however, paleontologists recognized that the Burgess Shale exemplified the radiation of diverse life forms unlike anything in earlier time. Here was evolution in action, organisms over time responding to changing fortunes through natural experimentation in new body forms and different ecological niches.

But the fossil record then goes dark: the Cambrian-period innovations in life appeared to have few clear descendants. Many scientists thought that the likely explanation for this mysterious disappearance was that a major extinction had wiped out much of the distinctive Cambrian life. It seemed that the complex organisms emerging in the Cambrian had come to an abrupt demise, disappearing with few traces in the later fossil record.

Not everyone was convinced, however, and now a trove of 480-million-year-old fossils in Morocco appears to strike a blow to the idea of a major extinction. The international team of scientists who discovered the 1,500 fossils said their find shows that the dark stretch in the fossil record more probably reflects an absence of preservation of fossils over the previous 25 million years.

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Life in the Third Realm
By OLIVIA JUDSON, The New York Times, MAY 18, 2010

It’s that time of the month again. Yes: it’s time for Life-form of the Month. In case you’ve forgotten, this coming Saturday is International Day for Biological Diversity, a day of celebrations and parties to appreciate the other occupants of the planet. So if you do nothing else this weekend, drink a toast to “Other Life-forms!” In honor of this event, my nomination for Life-form of the Month: May is a group of abundant and fascinating beings that are undeservedly obscure: the archaea.

Say who?

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High-Tech Tour of the Caves of Nottingham
By SINDYA N. BHANOO, The New York Times, May 17, 2010

Legend has it that Robin Hood was captured by the Sheriff of Nottingham and then imprisoned in the sandstone caves that lie beneath the city.

Whether Robin Hood was real or mythological is debatable, but the caves of Nottingham, carved into soft sandstone, do exist. Throughout the city, under modern day homes and businesses and the Nottingham Castle, there is a labyrinth of medieval tunnels, dungeons and cellars. Now, using laser technology, researchers are collecting 500,000 data points a second, measuring the size and scope of the caves at a pace that was not previously possible.

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The Science of a Happy Marriage
By TARA PARKER-POPE, The New York Times, May 10, 2010

Why do some men and women cheat on their partners while others resist the temptation?

To find the answer, a growing body of research is focusing on the science of commitment. Scientists are studying everything from the biological factors that seem to influence marital stability to a person’s psychological response after flirting with a stranger.

Their findings suggest that while some people may be naturally more resistant to temptation, men and women can also train themselves to protect their relationships and raise their feelings of commitment.

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Mapping Ancient Civilization, in a Matter of Days
By JOHN NOBLE WILFORD, The New York Times, May 10, 2010

For a quarter of a century, two archaeologists and their team slogged through wild tropical vegetation to investigate and map the remains of one of the largest Maya cities, in Central America. Slow, sweaty hacking with machetes seemed to be the only way to discover the breadth of an ancient urban landscape now hidden beneath a dense forest canopy.

Even the new remote-sensing technologies, so effective in recent decades at surveying other archaeological sites, were no help. Imaging radar and multispectral surveys by air and from space could not “see” through the trees.

Then, in the dry spring season a year ago, the husband-and-wife team of Arlen F. Chase and Diane Z. Chase tried a new approach using airborne laser signals that penetrate the jungle cover and are reflected from the ground below. They yielded 3-D images of the site of ancient Caracol, in Belize, one of the great cities of the Maya lowlands.

In only four days, a twin-engine aircraft equipped with an advanced version of lidar (light detection and ranging) flew back and forth over the jungle and collected data surpassing the results of two and a half decades of on-the-ground mapping, the archaeologists said. After three weeks of laboratory processing, the almost 10 hours of laser measurements showed topographic detail over an area of 80 square miles, notably settlement patterns of grand architecture and modest house mounds, roadways and agricultural terraces.

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A Bottom Feeder Leaves Traces Below
By SINDYA N. BHANOO, The New York Times, May 10, 2010

The series of squiggles and little ovals were perplexing, at first.

But it was only a matter of time before Anthony Martin, a fossil trace expert, deciphered the fossil’s code, and used it to tell the story of a fish that lived 50 million years ago in Wyoming’s Fossil Lake and swam at depths previously thought to be too deep for a fish to breathe in.

The squiggles were impressions of the fish’s fins, sweeping across the lake’s bottom, said Dr. Martin, a professor in the department of environmental studies at Emory University.

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Fruit Fly Gender Varies at the Cellular Level
By SINDYA N. BHANOO, The New York Times, May 10, 2010

Thirty years ago, the biologist Bruce S. Baker discovered that the gender of a fruit fly is determined not by a hormone, but by the expression of a gene called doublesex in individual cells. Female fruit flies express one form of the gene in their cells, while males express another.

Now, with the help of DNA technology, Dr. Baker and his colleagues have made a surprising discovery: not every cell in the fly is marked as male or female.

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Maternal Health: A New Study Challenges Benefits of Vitamin A for Women and Babies
By DONALD G. McNEIL Jr., The New York Times, May 3, 2010

Giving women vitamin A capsules did not save their lives or the lives of their new babies, according to a surprising new study from Ghana reported this week by the medical journal Lancet.

The results contradicted an earlier study in Nepal that showed a huge drop in deaths among child-bearing women taking vitamin A, and disappointed experts who hoped pills could be a cheap, easy lifesaver. Scientists did establish in the 1980s that giving vitamin A to malnourished children prevented stunting and deaths from measles and diarrhea.

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Mammoth Hemoglobin Offers More Clues to Its Arctic Evolution
By NICHOLAS WADE, The New York Times, May 3, 2010

For the first time in 43,000 years, a woolly mammoth has breathed again on earth.

Well, not the mammoth itself but its hemoglobin, the stuff in red blood cells that takes on oxygen in the lungs and offloads it in the tissues. By reconstructing the mammoth’s hemoglobin, a team led by Kevin L. Campbell of the University of Manitoba in Canada has discovered how the once-tropical species adapted to living in arctic temperatures.

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Farmers Cope With Roundup-Resistant Weeds
By WILLIAM NEUMAN and ANDREW POLLACK, May 3, 2010

DYERSBURG, Tenn. — For 15 years, Eddie Anderson, a farmer, has been a strict adherent of no-till agriculture, an environmentally friendly technique that all but eliminates plowing to curb erosion and the harmful runoff of fertilizers and pesticides.

But not this year.

On a recent afternoon here, Mr. Anderson watched as tractors crisscrossed a rolling field — plowing and mixing herbicides into the soil to kill weeds where soybeans will soon be planted.

Just as the heavy use of antibiotics contributed to the rise of drug-resistant supergerms, American farmers’ near-ubiquitous use of the weedkiller Roundup has led to the rapid growth of tenacious new superweeds.

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When the Ties That Bind Unravel
By TARA PARKER-POPE, The New York Times, May 3, 2010

Therapists for years have listened to patients blame parents for their problems. Now there is growing interest in the other side of the story: What about the suffering of parents who are estranged from their adult children?

While there are no official tallies of parents whose adult children have cut them off, there is no shortage of headlines. The Olympic gold medal skier Lindsey Vonn reportedly hasn’t spoken to her father in at least four years. The actor Jon Voight and his daughter, Angelina Jolie, were photographed together in February for the first time since they were estranged in 2002.

A number of Web sites and online chat rooms are devoted to the issue, with heartbreaking tales of children who refuse their parents’ phone calls and e-mail and won’t let them see grandchildren. Some parents seek grief counseling, while others fall into depression and even contemplate suicide.

Joshua Coleman, a San Francisco psychologist who is an expert on parental estrangement, says it appears to be growing more and more common, even in families who haven’t experienced obvious cruelty or traumas like abuse and addiction. Instead, parents often report that a once-close relationship has deteriorated after a conflict over money, a boyfriend or built-up resentments about a parent’s divorce or remarriage.

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Like Origami, Pollen Grains Fold Just So
By HENRY FOUNTAIN, The New York Times, April 26, 2010

After it is released from a flower’s anther, a pollen grain walks a humidity tightrope. It dries up a bit as it travels through the air, the cellular material inside becoming dormant so it survives until it reaches the humid environment of another flower’s stigma. But it can’t become so dry that the material dies.

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Three-Spined Stickleback Proves a Purposeful Cannibal
By HENRY FOUNTAIN, The New York Times, April 26, 2010

It’s a fact of life in the animal world that some fish (and birds, mammals, reptiles, insects, crustaceans — you name it) eat their young.

The three-spined stickleback, a species found around much of the globe, is one such finned filial cannibal. The males, who care for the eggs, are known to devour whole or parts of clutches. Sometimes, however, they might have reason to — since sticklebacks are known to “sneak” fertilizations, another fish might be the father of some of the eggs.

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Exploring the Complexities of Nerdiness, for Laughs
By DENNIS OVERBYE, The New York Times, April 26, 2010

BURBANK, Calif. — Shudders and groans went around the blogs and coffee rooms of the physics world back in the summer of 2007, when CBS announced plans for a new comedy series about a pair of nerdy physicists and their buxom blonde waitress neighbor.

After all, the characters, Sheldon Cooper, a gangly supremely confident theoretical physicist at a place a lot like the California Institute of Technology, who has an IQ of 187 and entered college at 11, and his roommate, Leonard Hofstadter, whose IQ is only slightly less lofty at 173, and who is instantly smitten by the waitress next door, would seem to embody all the stereotypes that scientists have come to hate: physicists are geeky losers, overwhelmingly male and ill at ease outside of the world of Star Trek.

Not to mention their pals Rajesh Koothrappali, who literally cannot speak in the presence of a pretty woman, and Howard Wolowitz, who can’t shut up, and Penny, who works at the Cheesecake Factory and doesn’t seem to know Newton the Isaac from Newton the fig.

Three years later some scientists still say that although the series, “The Big Bang Theory” (Monday nights on CBS), is funny and scientifically accurate, they are put off by it.

“Makes me cringe,” said Bruce Margon, an astrophysicist at the University of California, Santa Cruz, explaining, “The terrible stereotyping of the nerd plus the dumb blond are steps backwards for science literacy.”

But other scientists are lining up for guest slots on the show, which has become one of highest rated comedies on television and won many awards. The Nobel laureate George Smoot of the University of California, Berkeley, and the NPR Science Friday host Ira Flatow, have appeared on the show.

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Lots of good ones this week!




Caesarean Births Are at an All Time High in U.S.
By DENISE GRADY, The New York Times, March 23, 2010

The Caesarean section rate in the United States reached 32 percent in 2007, the country’s highest rate ever, health officials are reporting.

The rate has been climbing steadily since 1996, setting new records year after year, and Caesarean section has become the most common operation in American hospitals. About 1.4 million Caesareans were performed in 2007, the latest year for which data is available.

The figures are being published online on Tuesday by the National Center for Health Statistics.

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Sabotaging Success, but to What End?
By RICHARD A. FRIEDMAN, M.D., The New York Times, March 22, 2010

“You could say I’ve been unlucky in love,” a young man told me during a recent consultation.

He went on to describe a series of failed romantic relationships, all united by a single theme: he had been mistreated by unsympathetic women who cheated on him.

This was not his only area of disappointment, though. At work, he had just been passed over for a promotion; it went to a colleague whom he viewed as inferior.

I asked him about his work as a computer scientist and discovered that he worked long hours and relished challenging problems. But he also did some curious things to undermine himself. Once, for example, he “forgot” about an important presentation and arrived 30 minutes late, apologizing profusely.

What was striking about this intelligent and articulate young man was his view that he was a hapless victim of bad luck, in the guise of unfaithful women and a capricious boss; there was no sense that he might have had a hand in his own misfortune.

I decided to push him. “Do you ever wonder why so many disappointing things happen to you?” I asked. “Is it just chance, or might you have something to do with it?”

His reply was a resentful question: “You think it’s all my fault, don’t you?”

Now I got it. He was about to turn our first meeting into yet another encounter in which he was mistreated. It seemed he rarely missed an opportunity to feel wronged.

Of all human psychology, self-defeating behavior is among the most puzzling and hard to change. After all, everyone assumes that people hanker after happiness and pleasure. Have you ever heard of a self-help book on being miserable?

So what explains those men and women who repeatedly pursue a path that leads to pain and disappointment? Perhaps there is a hidden psychological reward.

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When Your Looks Take Over Your Life
By JANE E. BRODY, The New York Times, March 22, 2010

Is there a part of you that you hate to look at and perhaps try to hide from others? Do you glance at your image in distress whenever you pass a reflective surface?

Many of us are embarrassed by or dissatisfied with some body part or other. I recall that from about age 11 through my early teens I sat in class with my hand over what I thought was an ugly bump on my nose. And I know a young woman of normal weight who refuses to sit down in a subway car because she thinks it makes her thighs look huge.

But what if such self-consciousness about a perceived facial or body defect becomes all consuming, an obsession or paranoia that keeps the person from focusing on school or work, pursuing normal social activities, even leaving the house to shop or see a doctor? What if it leads to attempted suicide?

Such are the challenges facing tens of thousands of Americans who suffer from body dysmorphic disorder, or B.D.D., a syndrome known for more than a century but recognized only recently by the official psychiatric diagnostic manual. Even more recently, effective treatments have been developed for the disorder, and its emotional and neurological underpinnings have begun to yield to research.

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Artists Mine Scientific Clues to Paint Intricate Portraits of the Past
By CARL ZIMMER, The New York Times, March 22, 2010

Somewhere in England, about 600 years ago, an artist sat down and tried to paint an elephant. There was just one problem: he had never seen one.

The artist was illustrating a book known today as the “Bestiary of Anne Walshe,” a guide to animals. To paint an elephant, he could not jet to Kenya to scrutinize one in person. He could not visit the London zoo. He could not watch a David Attenborough DVD or click through a Web gallery of nature photographs. The only clues the artist could have found were in the mix of facts and myths preserved in old books.

There he might read how elephants cannot bend at the knees, or that they have no interest in sex. There were illustrations of elephants in those old books, too, but they were painted by artists who had also never seen one. In the end, the illustrator of the “Bestiary of Anne Walshe” produced a charming mishmash of guesses. His elephant looks like a bull terrier with camel hooves for feet and a vacuum cleaner for a nose.

Artists are still painting things they cannot see in real life. Rather than being separated from their subjects by thousands of miles, though, today’s artists are separated by thousands of years — even millions of them. Fortunately, they have a lot more scientific information on which to base their images. But they cannot eliminate the gap between reality and image.

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After Years of War and Abuse, New Hope for Ancient Babylon
By JOHN NOBLE WILFORD, The New York Times, March 22, 2010

The most immediate threat to preserving the ruins of Babylon, the site of one of the Seven Wonders of the Ancient World, is water soaking the ground and undermining what is left in present-day Iraq of a great city from the time of King Nebuchadnezzar II.

It is also one of the oldest threats. The king himself faced water problems 2,600 years ago. Neglect, reckless reconstruction and wartime looting have also taken their toll in recent times, but archaeologists and experts in the preservation of cultural relics say nothing substantial should be done to correct that until the water problem is brought under control.

A current study, known as the Future of Babylon project, documents the damage from water mainly associated with the Euphrates River and irrigation systems nearby. The ground is saturated just below the surface at sites of the Ishtar Gate and the long-gone Hanging Gardens, one of the seven wonders. Bricks are crumbling, temples collapsing. The Tower of Babel, long since reduced to rubble, is surrounded by standing water.

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For Extinct Monsters of the Deep, a Little Respect
By SEAN B. CARROLL, The New York Times, March 22, 2010

Here is a quick paleontology quiz. Which group of animals included large, air-breathing predators up to 50 feet long that bore live young, dominated their world for more than 100 million years and were ultimately exterminated by an asteroid 65 million years ago?

Easy, right?

Did you say dinosaurs? Sorry, wrong answer. But it was a trickier question than it may have appeared.

The correct answer is marine reptiles, which at the time of the last great extinction included mosasaurs, plesiosaurs and pliosaurs. The key clue in my question was “bore live young.” Unlike the dinosaurs, which were terrestrial and laid eggs, marine reptiles were fully aquatic and bore live young. This latter combination was no coincidence.

Despite their awesome size and abundance in the fossil record — their bones were among the first to be recognized as fossil remains of extinct creatures — marine reptiles have long played second fiddle to their much more famous saurian cousins.

But if we humans were aquatic creatures, we would have a whole lot more respect for these other reptiles. They were the top predators of Cretaceous seas. Thanks to their prevalence, scientists have figured out a lot about them, particularly recently. This includes, most remarkably, insights into their genetics — something that is not even preserved in the fossil record — and what it took to transform ordinary lizards into extraordinary sea monsters.

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A Host of Mummies, a Forest of Secrets
By NICHOLAS WADE, The New York Times, March 15, 2010

In the middle of a terrifying desert north of Tibet, Chinese archaeologists have excavated an extraordinary cemetery. Its inhabitants died almost 4,000 years ago, yet their bodies have been well preserved by the dry air.

The cemetery lies in what is now China’s northwest autonomous region of Xinjiang, yet the people have European features, with brown hair and long noses. Their remains, though lying in one of the world’s largest deserts, are buried in upside-down boats. And where tombstones might stand, declaring pious hope for some god’s mercy in the afterlife, their cemetery sports instead a vigorous forest of phallic symbols, signaling an intense interest in the pleasures or utility of procreation.

The long-vanished people have no name, because their origin and identity are still unknown. But many clues are now emerging about their ancestry, their way of life and even the language they spoke.

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Answers Begin to Emerge on How Thalidomide Caused Defects
By CARL ZIMMER, The New York Times, March 15, 2010

The word “phocomelia” means seal limb. It describes an extremely rare condition in which babies are born with limbs that look like flippers.

The long bones of the arms fail to develop, but fingers sometimes sprout from the shoulders. In some cases, the legs fail to develop, too. The French anatomist Étienne Geoffroy Saint-Hilaire coined the word in 1836, and it immediately sank into scientific obscurity for 120 years. And then, 50 years ago, it suddenly became all too familiar.

Doctors began to see more and more cases. It turned out that a drug called thalidomide, which pregnant women were taking for morning sickness, was responsible. Magazines and newspapers ran shocking pictures of seal-limbed children, and the drug was banned in 1962. By then, 10,000 children, mostly in Europe, had been born with thalidomide-induced birth defects.

Despite the notoriety, phocomelia remained scientifically mysterious for the next five decades. Doctors knew all too well to avoid thalidomide, but developmental biologists could not explain how thalidomide made limbs disappear.

Only now are scientists finally starting to solve the puzzle. And by deciphering thalidomide’s effects, they are discovering surprising clues about how normal limbs develop. They hope that those fundamental insights will in turn produce a medical benefit.

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Obama’s C.D.C. Director, Wielding a Big Broom
By GARDINER HARRIS, The New York Times, March 15, 2010

ATLANTA — No federal health agency changed more during the Bush administration than the Centers for Disease Control and Prevention. It got new buildings, new managers and an entirely new operating structure.

A year into the Obama administration, only the new buildings remain. Dr. Thomas R. Frieden, the agency’s director since June, has quietly scrapped nearly all the administrative changes that the previous director, Dr. Julie L. Gerberding, spent much of her six-year tenure conceiving and carrying out.

Gone are the nonscientific managers whom Dr. Gerberding sprinkled throughout the agency’s top ranks. Gone is a layer of bureaucracy, agency officials said. Gone, too, are the captain’s chairs with cup holders from a conference room so fancy that agency managers dubbed it the Crown Room.

In their place, Dr. Frieden has restored not only much of the agency’s previous organizational structure and scientific managers, but also its drab furniture. And he has brought something new: a frenetic sense of urgency.

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Scientists Strive to Map the Shape-Shifting Net
By JOHN MARKOFF, The New York Times, March 2, 2010

SAN FRANCISCO — In a dimly lit chamber festooned with wires and hidden in one of California’s largest data centers, Tim Pozar is changing the shape of the Internet.

He is using what Internet engineers refer to as a “meet-me room.” The room itself is enclosed in a building full of computers and routers. What Mr. Pozar does there is to informally wire together the networks of different businesses that want to freely share their Internet traffic.

The practice is known as peering, and it goes back to the earliest days of the Internet, when organizations would directly connect their networks instead of paying yet another company to route data traffic. Originally, the companies that owned the backbone of the Internet shared traffic. In recent years, however, the practice has increased to the point where some researchers who study the way global networks are put together believe that peering is changing the fundamental shape of the Internet, with serious consequences for its stability and security. Others see the vast increase in traffic staying within a structure that has remained essentially the same.

What is clear is that today a significant portion of Internet traffic does not flow through the backbone networks of giant Internet companies like AT&T and Level 3. Instead, it has begun to cascade in torrents of data on the edges of the network, as if a river in flood were carving new channels.

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Human Culture, an Evolutionary Force
By NICHOLAS WADE, The New York Times, March 2, 2010

As with any other species, human populations are shaped by the usual forces of natural selection, like famine, disease or climate. A new force is now coming into focus. It is one with a surprising implication — that for the last 20,000 years or so, people have inadvertently been shaping their own evolution.

The force is human culture, broadly defined as any learned behavior, including technology. The evidence of its activity is the more surprising because culture has long seemed to play just the opposite role. Biologists have seen it as a shield that protects people from the full force of other selective pressures, since clothes and shelter dull the bite of cold and farming helps build surpluses to ride out famine.

Because of this buffering action, culture was thought to have blunted the rate of human evolution, or even brought it to a halt, in the distant past. Many biologists are now seeing the role of culture in a quite different light.

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BASICS: Bringing New Understanding to the Director’s Cut
By NATALIE ANGIER, The New York Times, March 2, 2010

And now, just in time for Oscar junkies, comes a new statistical mincing of the movies that may someday yield an award category of its own: best fit between a movie’s tempo and the natural rhythms of the brain.

Reporting in the journal Psychological Science, James E. Cutting of Cornell University and his colleagues described their discovery that Hollywood filmmakers, whether they know it or not, have become steadily more adroit at shaping basic movie structure to match the pulsatile, half-smooth, half-raggedy way we attend to the world around us. This mounting synchrony between movie pace and the bouncing ball of the mind’s inner eye may help explain why today’s films manage to seize and shackle audience attention so ruthlessly and can seem more lifelike and immediate than films of the past, even when the scripts are lousier and you feel cheap and used afterward, not to mention vaguely sick from the three-quart tub of popcorn and pack of Twizzlers you ate without realizing it.

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In Obesity Epidemic, What’s One Cookie?
By TARA PARKER-POPE, The New York Times, MARCH 1, 2010

The basic formula for gaining and losing weight is well known: a pound of fat equals 3,500 calories.

That simple equation has fueled the widely accepted notion that weight loss does not require daunting lifestyle changes but “small changes that add up,” as the first lady, Michelle Obama, put it last month in announcing a national plan to counter childhood obesity.

In this view, cutting out or burning just 100 extra calories a day — by replacing soda with water, say, or walking to school — can lead to significant weight loss over time: a pound every 35 days, or more than 10 pounds a year.

While it’s certainly a hopeful message, it’s also misleading. Numerous scientific studies show that small caloric changes have almost no long-term effect on weight. When we skip a cookie or exercise a little more, the body’s biological and behavioral adaptations kick in, significantly reducing the caloric benefits of our effort.

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Findings: When It Comes to Salt, No Rights or Wrongs. Yet.
By JOHN TIERNEY, The New York Times, February 23, 2010

Suppose, as some experts advise, that the new national dietary guidelines due this spring will lower the recommended level of salt. Suppose further that public health officials in New York and Washington succeed in forcing food companies to use less salt. What would be the effect?

A) More than 44,000 deaths would be prevented annually (as estimated recently in The New England Journal of Medicine).

B) About 150,000 deaths per year would be prevented annually (as estimated by the New York City Department of Health and Mental Hygiene).

C) Hundreds of millions of people would be subjected to an experiment with unpredictable and possibly adverse effects (as argued recently in The Journal of the American Medical Association).

D) Not much one way or the other.

E) Americans would get even fatter than they are today.

Don’t worry, there’s no wrong answer, at least not yet. That’s the beauty of the salt debate: there’s so little reliable evidence that you can imagine just about any outcome. For all the talk about the growing menace of sodium in packaged foods, experts aren’t even sure that Americans today are eating more salt than they used to.

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Observatory: Puzzle Solved: How a Fatherless Lizard Species Maintains Its Genetic Diversity
By SINDYA N. BHANOO, The New York Times, February 23, 2010

More than 40 years ago, Bill Neaves, then a young Ph.D. student, discovered how an all-female, asexual species of the whiptail lizard came to be. He found that the lizard was a cross between the female species of one type of lizard and the male species of another.

But what has puzzled him for years is how this all-female species maintains its high level of genetic variation, a contribution to evolutionary fitness that typically comes from sexual reproduction.

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Observatory: Crickets Warn Young Before Birth of Dangers of Wolf Spiders
By SINDYA N. BHANOO, The New York Times, February 23, 2010

If an expectant mother knew that dangerous creatures lurked around her, and knew also that she wouldn’t be around to take care of her young, she might be stressed.

And if she had a way to warn her young before they were born, surely she would.

Human mothers cannot do this, to the best of our knowledge. But pregnant crickets, it appears, do have the ability to forewarn. This is especially useful since crickets abandon their young after birth.

Researchers from the University of South Carolina Upstate and Indiana State University placed pregnant crickets in an enclosure where they were stalked, but not eaten, by a wolf spider, whose fangs had been coated with wax to protect the crickets.

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Mind: Evidence That Little Touches Do Mean So Much
By BENEDICT CAREY, The New York Times, February 23, 2010

Psychologists have long studied the grunts and winks of nonverbal communication, the vocal tones and facial expressions that carry emotion. A warm tone of voice, a hostile stare — both have the same meaning in Terre Haute or Timbuktu, and are among dozens of signals that form a universal human vocabulary.

But in recent years some researchers have begun to focus on a different, often more subtle kind of wordless communication: physical contact. Momentary touches, they say — whether an exuberant high five, a warm hand on the shoulder, or a creepy touch to the arm — can communicate an even wider range of emotion than gestures or expressions, and sometimes do so more quickly and accurately than words.

“It is the first language we learn,” said Dacher Keltner, a professor of psychology at the University of California, Berkeley, and the author of “Born to Be Good: The Science of a Meaningful Life” (Norton, 2009), and remains, he said, “our richest means of emotional expression” throughout life.

The evidence that such messages can lead to clear, almost immediate changes in how people think and behave is accumulating fast. Students who received a supportive touch on the back or arm from a teacher were nearly twice as likely to volunteer in class as those who did not, studies have found. A sympathetic touch from a doctor leaves people with the impression that the visit lasted twice as long, compared with estimates from people who were untouched. Research by Tiffany Field of the Touch Research Institute in Miami has found that a massage from a loved one can not only ease pain but also soothe depression and strengthen a relationship.

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Wanted: Volunteers, All Pregnant
By PAM BELLUCK, The New York Times, February 16, 2010

The woman sent by government scientists visited the Queens apartment repeatedly before finding anyone home. And the person who finally answered the door — a 30-year-old Colombian-born waitress named Alejandra — was wary.

Although Alejandra was exactly what the scientists were looking for — a pregnant woman — she was “a bit scared,” she said, about giving herself and her unborn child to science for 21 years.

Researchers would collect and analyze her vaginal fluid, toenail clippings, breast milk and other things, and ask about everything from possible drug use to depression. At the birth, specimen collectors would scoop up her placenta and even her baby’s first feces for scientific posterity.

“Nowadays there are so many scams,” Alejandra said in Spanish, and her husband, José, “initially didn’t want me to do the study.” (Scientists said research confidentiality rules required that her last name be withheld.) But she ultimately decided that participating would “help the next generation.”

Chalk one up for the scientists, who for months have been dispatching door-to-door emissaries across the country to recruit women like Alejandra for an unprecedented undertaking: the largest, most comprehensive long-term study of the health of children, beginning even before they are born.

Authorized by Congress in 2000, the National Children’s Study began last January, its projected cost swelling to about $6.7 billion. With several hundred participants so far, it aims to enroll 100,000 pregnant women in 105 counties, then monitor their babies until they turn 21.

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On Crete, New Evidence of Very Ancient Mariners
By JOHN NOBLE WILFORD, The New York Times, February 16, 2010

Early humans, possibly even prehuman ancestors, appear to have been going to sea much longer than anyone had ever suspected.

That is the startling implication of discoveries made the last two summers on the Greek island of Crete. Stone tools found there, archaeologists say, are at least 130,000 years old, which is considered strong evidence for the earliest known seafaring in the Mediterranean and cause for rethinking the maritime capabilities of prehuman cultures.

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In Brookhaven Collider, Scientists Briefly Break a Law of Nature
By DENNIS OVERBYE, The New York Times, February 16, 2010

Physicists said Monday that they had whacked a tiny region of space with enough energy to briefly distort the laws of physics, providing the first laboratory demonstration of the kind of process that scientists suspect has shaped cosmic history.

The blow was delivered in the Relativistic Heavy Ion Collider, or RHIC, at the Brookhaven National Laboratory on Long Island, where, since 2000, physicists have been accelerating gold nuclei around a 2.4-mile underground ring to 99.995 percent of the speed of light and then colliding them in an effort to melt protons and neutrons and free their constituents — quarks and gluons. The goal has been a state of matter called a quark-gluon plasma, which theorists believe existed when the universe was only a microsecond old.

The departure from normal physics manifested itself in the apparent ability of the briefly freed quarks to tell right from left. That breaks one of the fundamental laws of nature, known as parity, which requires that the laws of physics remain unchanged if we view nature in a mirror.

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This King-Size Frog Hopped With Dinosaurs
By SINDYA N. BHANOO, February 16, 2010

STONY BROOK, N.Y. — Now appearing in the lobby of Stony Brook University Medical Center: a frog that lived in the era of the dinosaurs and is as big as a beach ball. Scientists believe it to be the largest frog ever.

The immense frog is part of a permanent exhibition that also features reconstructions of a vegetarian pug-nosed crocodile and a small meat-eating dinosaur.

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If You Swat, Watch Out: Bees Remember Faces
By SINDYA N. BHANOO, The New York Times, February 2, 2010

A honeybee brain has a million neurons, compared with the 100 billion in a human brain. But, researchers report, bees can recognize faces, and they even do it the same way we do.

Bees and humans both use a technique called configural processing, piecing together the components of a face — eyes, ears, nose and mouth — to form a recognizable pattern, a team of researchers report in the Feb. 15 issue of The Journal of Experimental Biology.

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The Miracle of Vitamin D: Sound Science, or Hype?
By TARA PARKER-POPE, The New York Times, FEBRUARY 1, 2010

Imagine a treatment that could build bones, strengthen the immune system and lower the risks of illnesses like diabetes, heart and kidney disease, high blood pressure and cancer.

Some research suggests that such a wonder treatment already exists. It’s vitamin D, a nutrient that the body makes from sunlight and that is also found in fish and fortified milk.

Yet despite the health potential of vitamin D, as many as half of all adults and children are said to have less than optimum levels and as many as 10 percent of children are highly deficient, according to a 2008 report in The American Journal of Clinical Nutrition.

As a result, doctors are increasingly testing their patients’ vitamin D levels and prescribing daily supplements to raise them. According to the lab company Quest Diagnostics, orders for vitamin D tests surged more than 50 percent in the fourth quarter of 2009, up from the same quarter a year earlier. And in 2008, consumers bought $235 million worth of vitamin D supplements, up from $40 million in 2001, according to Nutrition Business Journal.

But don’t start gobbling down vitamin D supplements just yet. The excitement about their health potential is still far ahead of the science.

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SECOND OPINION: A Lasting Gift to Medicine That Wasn’t Really a Gift
By DENISE GRADY, The New York Times, February 2, 2010

Fifty years after Henrietta Lacks died of cervical cancer in the “colored” ward at Johns Hopkins Hospital, her daughter finally got a chance to see the legacy she had unknowingly left to science. A researcher in a lab at Hopkins swung open a freezer door and showed the daughter, Deborah Lacks-Pullum, thousands of vials, each holding millions of cells descended from a bit of tissue that doctors had snipped from her mother’s cervix.

Ms. Lacks-Pullum gasped. “Oh God,” she said. “I can’t believe all that’s my mother.”

When the researcher handed her one of the frozen vials, Ms. Lacks-Pullum instinctively said, “She’s cold,” and blew on the tube to warm it. “You’re famous,” she whispered to the cells.

Minutes later, peering through a microscope, she pronounced them beautiful. But when she asked the researcher which were her mother’s normal cells and which the cancer cells, his answer revealed that her precious relic was not quite what it seemed. The cells, he replied, were “all just cancer.”

The vignette comes from a gripping new book, “The Immortal Life of Henrietta Lacks” (Crown Publishers), by the journalist Rebecca Skloot. The story of Mrs. Lacks and her cells, and the author’s own adventures with Mrs. Lacks’s grown children (one fries her a pork chop, and another slams her against a wall) is by turns heartbreaking, funny and unsettling. The book raises troubling questions about the way Mrs. Lacks and her family were treated by researchers and about whether patients should control or have financial claims on tissue removed from their bodies.

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BOOKS ON SCIENCE: Tale of an Unsung Fossil Finder, in Fact and Fiction
By KATHERINE BOUTON, The New York Times, February 2, 2010

THE FOSSIL HUNTER: Dinosaurs, Evolution and the Woman Whose Discoveries Changed the World.
By Shelley Emling. Palgrave Macmillan. 234 pages. $27.

REMARKABLE CREATURES
By Tracy Chevalier. Dutton. 312 pages. $26.95.


Mary Anning was one of the few women to make a success in paleontology and one of the fewer still whose success was not linked to that of a paleontologist spouse (or any spouse: she was single). She made five major fossil discoveries from 1811 to her death in 1847, and many lesser ones.

Why then is she best known as the inspiration for the tongue twister “She sells sea shells by the seashore”?

The answer lies in her gender, her poverty, her lack of formal education, her regional accent — as it might even today. But as Shelley Emling says in “The Fossil Hunter,” her readable biography of Anning, she had one major advantage in the place and time of her birth: Lyme Regis, 1799.

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FINDINGS: Corporate Backing for Research? Get Over It
By JOHN TIERNEY, The New York Times, January 26, 2010

I find myself in the unfamiliar position of defending Al Gore and his fellow Nobel laureate, Rajendra K. Pachauri.

When they won the prize in 2007, they were hailed for their selfless efforts to protect the planet from the ravages of greedy fossil fuel industries. Since then, though, their selflessness has been questioned. Journalists started by looking at the money going to companies and nonprofit groups associated with Mr. Gore, and now they have turned their attention to Dr. Pauchauri, the chairman of the United Nations Intergovernmental Panel on Climate Change.

The I.P.C.C., which is supposed to be the gold standard of peer-reviewed climate science, in 2007 warned of a “very high” likelihood that global warming would cause the Himalayan glaciers to disappear by 2035. When the Indian government subsequently published a paper concluding there was no solid evidence of Himalayan glaciers shrinking because of global warming, Dr. Pachauri initially dismissed it as “voodoo science” beneath the I.P.C.C.’s standards.

But then it came out that the I.P.C.C.’s projection was based not on the latest peer-reviewed evidence, but on speculative comments made a decade ago in a magazine interview by Syed Hasnain, a glaciologist who now works in an Indian research group led by Dr. Pachauri.

Last week, the I.P.C.C apologized for the mistake, which was embarrassing enough for Dr. Pachauri. But he also had to contend with accusations of conflict of interest. The Telegraph of London reported that he had a “worldwide portfolio of business interests,” which included relationships with carbon-trading companies and his research group, the Energy and Resources Institute.

Dr. Pachauri responded with a defense of his ethics, saying that he had not profited personally and that he had directed all revenues to his nonprofit institute. He denounced his critics’ tactics: “You can’t attack the science, so attack the chair of the I.P.C.C.”

I can’t defend that entire sentiment, because you obviously can attack some of the science in the I.P.C.C. report, not to mention other dire warnings in Dr. Pachauri’s speeches.

But I do agree with his basic insight: Conflict-of-interest accusations have become the simplest strategy for avoiding a substantive debate. The growing obsession with following the money too often leads to nothing but cheap ad hominem attacks.

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A New Way to Look for Diseases’ Genetic Roots
By NICHOLAS WADE, January 26, 2010

The hunt for the genetic roots of common diseases has hit a blank wall.

The genetic variants found so far account in most cases for a small fraction of the genetic risk of the major killers. So where is the missing heritability and why has it not showed up?

A Duke geneticist now suggests that the standard method of gene hunting had a theoretical flaw and should proceed on a different basis. The purpose of the $3 billion project to decode the human genome, completed in 2003, was to discover the genetic roots of common diseases like diabetes, cancer and Alzheimer’s. The diseases are called complex, meaning that several mutated genes are probably implicated in each.

A principal theory has long been that these variant genes have become common in the population because the diseases strike late in life, after a person has had children. Bad genes would not be eliminated by natural selection at that age, as they would if the diseases struck before the child-bearing years.

So to find disease genes, the thinking went, do not decode the entire genome of every patient — just look at the few sites where genetic variations are common, defined as being present in at least 1 percent of the population.

These sites of common variation are called SNPs (pronounced “snips”), and biotech companies have developed ingenious devices to recognize up to 500,000 SNPs at a time. The SNP chips made possible genomewide association studies in which the genomes of many patients are compared with those of healthy people to see which SNPs are correlated with the disease.

The SNP chips worked well, the studies were well designed, though enormously expensive, and some 2,000 disease-associated SNPs have been identified by university consortiums in the United States and Europe.

But this mountainous labor produced something of a mouse.

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The Ozone Hole Is Mending. Now for the ‘But.’
By SINDYA N. BHANOO, The New York Times, January 26, 2010

That the hole in Earth’s ozone layer is slowly mending is considered a big victory for environmental policy makers. But in a new report, scientists say there is a downside: its repair may contribute to global warming.

It turns out that the hole led to the formation of moist, brighter-than-usual clouds that shielded the Antarctic region from the warming induced by greenhouse gas emissions over the last two decades, scientists write in Wednesday’s issue of Geophysical Research Letters.

“The recovery of the hole will reverse that,” said Ken Carslaw, a professor of atmospheric science at the University of Leeds and a co-author of the paper. “Essentially, it will accelerate warming in certain parts of the Southern Hemisphere.”

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GLOBAL UPDATE: Parasites: ‘Tropical’ Diseases Are Common in Arctic Dwellers, a Survey Finds
By DONALD G. McNEIL Jr., The New York Times, January 26, 2010

The kind of worm and protozoan infections that are often called neglected “tropical” diseases are also common among aboriginal peoples living in the Arctic, according to a recent survey.

Outbreaks of trichinosis, a larval-worm disease commonly associated with eating undercooked pork and carnivorous wild game, also occur among people who eat infected polar bear and walrus meat, and the Arctic harbors a unique species of the worm that can survive subzero temperatures. Mild infestations cause nausea and stomach pain; severe ones can kill.

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Genome Study Provides a Census of Early Humans
By NICHOLAS WADE, The New York Times, January 19, 2010

From the composition of just two human genomes, geneticists have computed the size of the human population 1.2 million years ago from which everyone in the world is descended.

They put the number at 18,500 people, but this refers only to breeding individuals, the “effective” population. The actual population would have been about three times as large, or 55,500.

Comparable estimates for other primates then are 21,000 for chimpanzees and 25,000 for gorillas. In biological terms, it seems, humans were not a very successful species, and the strategy of investing in larger brains than those of their fellow apes had not yet produced any big payoff. Human population numbers did not reach high levels until after the advent of agriculture.

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OBSERVATORY: The Platypus Is Cute but Far From Harmless
By HENRY FOUNTAIN, The New York Times, January 19, 2010

In “The Nutmeg of Consolation” by Patrick O’Brian, the 14th in his series of maritime novels, the good Dr. Stephen Maturin’s unabashed joy at finally seeing a platypus in Australia is almost immediately tempered by the incapacitating pain he experiences when he is stung by poisonous spurs on the animal’s rear legs.

Dr. Maturin could be forgiven if he didn’t know that the platypus is among the few mammals that produce venom (and with platypuses, only the male does). Even those who know about platypus venom do not really know much about it.

They know a little more now. Researchers in Japan have identified some of the constituents of the venom that may help make it so painful.

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Ancient Egypt’s Toxic Makeup Fought Infection, Researchers Say
By SINDYA N. BHANOO, The New York Times, January 19, 2010

The elaborate eye makeup worn by Queen Nefertiti and other ancient Egyptians was believed to have healing powers, conjuring up the protection of the Gods Horus and Ra and warding off illnesses.

Science does not allow for magic, but it does allow for healing cosmetics. The lead-based makeup used by the Egyptians had antibacterial properties that helped prevent infections common at the time, according to a report published Friday in Analytical Chemistry, a semimonthly journal of the American Chemical Society.

“It was puzzling; they were able to build a strong, rich society, so they were not completely crazy,” said Christian Amatore, a chemist at the École Normale Supérieure in Paris and one of the paper’s authors. “But they believed this makeup was healing — they said incantations as they mixed it, things that today we call garbage.”

Dr. Amatore and his fellow researchers used electron microscopy and X-ray diffraction to analyze 52 samples from containers of Egyptian makeup preserved at the Louvre.

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Researchers have been using Dungeons & Dragons dice to learn how to pack tetrahedrons. The record density recently hit 85.63 percent.

Packing Tetrahedrons, and Closing in on a Perfect Fit
By KENNETH CHANG, The New York Times, January 5, 2010

More than 2,300 years ago, Aristotle was wrong.

Now, in the past year, a flurry of academic activity is suddenly zooming in on an answer to a problem akin to wondering how many people can fit into a Volkswagen Beetle or a phone booth. Except here mathematicians have been thinking not about the packing of people, but of geometric solids known as tetrahedrons.

“It’s pretty remarkable how many papers have been written on this in the past year,” said Henry Cohn, a mathematician at Microsoft Research New England.

A tetrahedron is a simple construct — four sides, each a triangle. For the packing problem, researchers are looking at so-called regular tetrahedrons, where each side is an identical equilateral triangle. Players of Dungeons & Dragons recognize the triangular pyramid shape as that of some dice used in the game.

Aristotle mistakenly thought that identical regular tetrahedrons packed together perfectly, as identical cubes do, leaving no gaps in between and filling 100 percent of the available space. They do not, and 1,800 years passed before someone pointed out that he was wrong. Even after that, the packing of tetrahedrons garnered little interest. More centuries passed.

A similar conundrum for how to best pack identical spheres has a more storied history. There, the answer was obvious. They should be stacked like oranges at a supermarket (with a packing density of 74 percent), and that is what Johannes Kepler conjectured in 1611. But proving the obvious took almost four centuries until Thomas C. Hales, a mathematician at the University of Pittsburgh, succeeded in 1998 with the help of a computer.

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OBSERVATORY: Much-Maligned Mother of Many Beloved Wines
By HENRY FOUNTAIN, The New York Times, January 5, 2010

About a decade ago, researchers had some startling news for wine lovers. Some of their beloved grape varieties, including chardonnay and gamay noir, were the offspring of a third-rate parent, gouais blanc. In fact, the research showed that at least a dozen varieties were a result of crosses, a long time ago, between pinot noir and gouais blanc, which had such a bad reputation that its cultivation was at times outlawed.

The news just got a bit more startling. Looking at the DNA in chloroplasts in the 12 varieties, Harriet V. Hunt and Matthew C. Lawes of the University of Cambridge in England and colleagues set out to determine which was the paternal parent (supplying the pollen) and which was the maternal one (supplying the egg cells). Gouais blanc, they write in Biology Letters, was the mother of nine of the varieties: aligoté, auxerrois, franc noir, melon, bachet, sacy and romorantin, in addition to chardonnay and gamay noir.

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Several lizard species that are dark have developed white skin in the White Sands of New Mexico.

OBSERVATORY: White Lizards Evolve in New Mexico Dunes
By HENRY FOUNTAIN, The New York Times, January 5, 2010

The White Sands of New Mexico are a good place to study evolution in progress. One reason is that the terrain, gypsum dunes white as a sheet of paper, is so different from the surrounding area. Another is that the dunes formed only about 6,000 years ago.

“From an evolutionary perspective, that’s really the blink of an eye,” said Erica Bree Rosenblum, a professor at the University of Idaho who has been studying evolution at White Sands for much of the past decade. Her focus has been on three lizard species that elsewhere are dark skinned but in White Sands have each evolved a white-skinned variety that makes them hard to find. “It’s really obvious what’s happened,” Dr. Rosenblum said. “Everybody got white so that they could better escape from their predators.” It’s a great example of convergent evolution, of species independently acquiring the same traits.

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Q & A: Temperature and Exercise
By C. CLAIBORNE RAY, The New York Times, January 5, 2010

Q. Does a person tend to burn more fat exercising outdoors in colder weather or in hotter weather? I am leaning to the colder weather side, since the body has to work harder to keep the body temperature near normal.

A. “Contrary to conventional wisdom, the combination of exercise and cold exposure does not act synergistically to enhance metabolism of fats,” according to a study published in 1991 in the journal Sports Medicine.

The study, done at the Hyperbaric Environmental Adaptation Program of the Naval Medical Research Institute in Bethesda, Md., found that some of the bodily processes involved in fat metabolism were actually slowed down by the effects of relatively cold temperatures on human tissue.

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A satellite image of the East Siberian Sea from 1999-2008. This image has been degraded to hide the satellite’s true capabilities.

C.I.A. Is Sharing Data With Climate Scientists
By William J. Broad, The New York Times, January 5, 2010

The nation’s top scientists and spies are collaborating on an effort to use the federal government’s intelligence assets — including spy satellites and other classified sensors — to assess the hidden complexities of environmental change. They seek insights from natural phenomena like clouds and glaciers, deserts and tropical forests.

The collaboration restarts an effort the Bush administration shut down and has the strong backing of the director of the Central Intelligence Agency. In the last year, as part of the effort, the collaborators have scrutinized images of Arctic sea ice from reconnaissance satellites in an effort to distinguish things like summer melts from climate trends, and they have had images of the ice pack declassified to speed the scientific analysis.

The trove of images is “really useful,” said Norbert Untersteiner, a professor at the University of Washington who specializes in polar ice and is a member of the team of spies and scientists behind the effort.

Scientists, Dr. Untersteiner said, “have no way to send out 500 people” across the top of the world to match the intelligence gains, adding that the new understandings might one day result in ice forecasts.

“That will be very important economically and logistically,” Dr. Untersteiner said, arguing that Arctic thaws will open new fisheries and sea lanes for shipping and spur the hunt for undersea oil and gas worth hundreds of billions of dollars.

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Observatory: DNA Shifts Timeline for Mammoths’ Exit
By HENRY FOUNTAIN, The New York Times, December 22, 2009

Thousands of years ago in northwestern North America, large animal species, among them the woolly mammoth and the horse, became extinct. Among the proposed explanations for this is one known as the blitzkrieg hypothesis — that humans entering the region rapidly wiped the animals out through overhunting.

The validity of that explanation, and others, depends in parts on the timing of the extinctions. How many thousands of years ago did the animals disappear?

Until now, the answer to that question has been 13,000 to 15,000 years ago. But those dates come from the youngest reliably dated fossils that have been found, and who is to say there aren’t even younger fossils out there?

A new study has come up with a far different answer, using a far different technique.

Rather than dating actual fossils, the researchers analyzed DNA found in permanently frozen sediments at a site on the Yukon River in central Alaska. As they report in The Proceedings of the National Academy of Sciences, they found evidence that mammoths and horses were still around at least until 10,500 years ago, long after humans arrived.

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Observatory: Foraging Early Humans Did Not Pass Up Grains
By HENRY FOUNTAIN, The New York Times, December 22, 2009

Early humans were hunter-gatherers, but what did they gather? The easy stuff, archeologists say — roots, fruits and nuts. Until relatively late in the Pleistocene, which ended about 12,000 years ago, grains were thought to have been largely ignored by foraging humans, at least in part because they were difficult to process.

But Julio Mercader, an archeologist at the University of Calgary, has now found evidence from a cave in Mozambique that humans were eating sorghum grasses at least 105,000 years ago. The evidence was in the form of microscopic starch granules found on stone tools from the cave.

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Basics: Sorry, Vegans: Brussels Sprouts Like to Live, Too
By NATALIE ANGIER, The New York Times, December 22, 2009

I stopped eating pork about eight years ago, after a scientist happened to mention that the animal whose teeth most closely resemble our own is the pig. Unable to shake the image of a perky little pig flashing me a brilliant George Clooney smile, I decided it was easier to forgo the Christmas ham. A couple of years later, I gave up on all mammalian meat, period. I still eat fish and poultry, however and pour eggnog in my coffee. My dietary decisions are arbitrary and inconsistent, and when friends ask why I’m willing to try the duck but not the lamb, I don’t have a good answer. Food choices are often like that: difficult to articulate yet strongly held. And lately, debates over food choices have flared with particular vehemence.

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An illustrated reconstruction of the head of the newly discovered Triassic dinosaur Tawa hallae.

OBSERVATORY: Bones Show Early Divergence of Dinosaur Lineage
By HENRY FOUNTAIN, The New York Times, December 15, 2009

The early evolution of dinosaurs, in the late Triassic period, is fuzzy, to say the least. Paleontologists know that the first dinosaurs appeared about 230 million years ago, but fossil evidence is so spotty that it is unclear where and when the major lineages — theropods, sauropods and ornithischians — began to diverge.

Some excellent 215-million-year-old fossils unearthed in Ghost Ranch, in northern New Mexico, are helping to clarify things. The bones, of a theropod that the discoverers have named Tawa hallae, support the idea that the lineages diverged early on in the part of the supercontinent Pangea that is now South America.

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Did You Hear the One About the Former Scientist?
By KENNETH CHANG, The New York Times, December 15, 2009

A biologist walks into a comedy club...

Actually, the story begins earlier. A biologist who had abandoned academia and was working in San Francisco on contract as a computer programmer for Charles Schwab walked into a Laundromat ...

The former biologist was Tim Lee. After completing his undergraduate biology degree at the University of California, San Diego, he worked at the Scripps Institution of Oceanography for a while before he realized he needed a doctorate to do the interesting work. But by the time he finished his Ph.D. at the University of California, Davis, he had realized he hated academia.

“I just didn’t want to read any more papers,” Dr. Lee said. “I didn’t want to write any more papers.”

Dr. Lee then worked as a computer programmer, and he moved to San Francisco. During a vacation, he read memoirs of comedians like Bill Cosby, Bob Newhart and Jerry Seinfeld, and he wrote some jokes.

Then he walked into a Laundromat, which was holding an open microphone night for anyone who wanted to take a shot at being a comic. Dr. Lee told about a dozen jokes. Only four or five of them got laughs, but that was good enough for the host to offer some encouraging words.

Dr. Lee wrote more jokes. He went to more open mikes. He eventually got a paying gig — $35 from a comedy club in Santa Cruz, Calif. Along the way, he started telling science jokes, and he discovered that PowerPoint made a good comedy prop.

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Case Shined First Light on Abuse of Children
By HOWARD MARKEL, M.D., The New York Times, December 15, 2009

“Mamma has been in the habit of whipping and beating me almost every day,” the little girl testified. “She used to whip me with a twisted whip — a rawhide.

“I have now on my head two black-and-blue marks which were made by Mamma with the whip, and a cut on the left side of my forehead which was made by a pair of scissors in Mamma’s hand; she struck me with the scissors and cut me. ... I never dared speak to anybody, because if I did I would get whipped.”

If the words sound depressingly familiar, it is because they could have come from any number of recent news accounts — or, for that matter, popular entertainment, like the recently opened movie “Precious,” which depicts the emotional and sexual abuse of a Harlem girl.

In fact, though, the quotation is from the 1874 case of Mary Ellen McCormack, below, a self-possessed 10-year-old who lived on West 41st Street, in the Hell’s Kitchen section of Manhattan. It was Mary Ellen who finally put a human face on child abuse — and prompted a reformers’ crusade to prevent it and to protect its victims, an effort that continues to this day.

Tellingly, the case was brought by the American Society for the Prevention of Cruelty to Animals. In 1874, there were no laws protecting children from physical abuse from their parents. It was an era of “spare the rod and spoil the child,” and parents routinely meted out painful and damaging punishment without comment or penalty.

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PERSONAL BEST: Ready to Exercise? Check Your Watch
By GINA KOLATA, The New York Times, December 10, 2009

MY friend Jen Davis and I often run together in the morning because it can be easier to fit in a run before work than after. But we always thought we ran better in the evening.

Then I accidentally discovered something weird. I took a spinning class one Thursday night, and my heart rate, measured by a monitor strapped around my chest, soared. I don’t usually use a heart-rate monitor, but with stationary bikes, heart rate is pretty much the only way to know how hard you are working. And that night, my high heart rate told me it really was a tough workout.

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Q & A: Odor Eaters
By C. CLAIBORNE RAY, The New York Times, December 8, 2009

Q. How does stainless steel remove the odor of garlic or onion from your hands?

A. There are plenty of anecdotal reports that such odors are killed by washing your hands with a commercially produced piece of “stainless soap” or just a handy stainless steel object like a pot or a sink. There are also chemical explanations for how it might work. And then there are those who say it does not work at all. What there does not seem to be is a published scientific study of any size to prove or disprove the efficacy of the method.

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BASICS: The Circular Logic of the Universe
By NATALIE ANGIER, The New York Times, December 8, 2009

CIRCLING my way not long ago through the Vasily Kandinsky show now on display in the suitably spiral setting of the Guggenheim Museum, I came to one of the Russian master’s most illustrious, if misleadingly named, paintings: “Several Circles.”

Those “several” circles, I saw, were more like three dozen, and every one of them seemed to be rising from the canvas, buoyed by the shrewdly exuberant juxtapositioning of their different colors, sizes and apparent translucencies. I learned that, at around the time Kandinsky painted the work, in 1926, he had begun collecting scientific encyclopedias and journals; and as I stared at the canvas, a big, stupid smile plastered on my face, I thought of yeast cells budding, or a haloed blue sun and its candied satellite crew, or life itself escaping the careless primordial stew.

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A Lost European Culture, Pulled From Obscurity
By JOHN NOBLE WILFORD, The New York Times, December 1, 2009

Before the glory that was Greece and Rome, even before the first cities of Mesopotamia or temples along the Nile, there lived in the Lower Danube Valley and the Balkan foothills people who were ahead of their time in art, technology and long-distance trade.

For 1,500 years, starting earlier than 5000 B.C., they farmed and built sizable towns, a few with as many as 2,000 dwellings. They mastered large-scale copper smelting, the new technology of the age. Their graves held an impressive array of exquisite headdresses and necklaces and, in one cemetery, the earliest major assemblage of gold artifacts to be found anywhere in the world.

The striking designs of their pottery speak of the refinement of the culture’s visual language. Until recent discoveries, the most intriguing artifacts were the ubiquitous terracotta “goddess” figurines, originally interpreted as evidence of the spiritual and political power of women in society.

New research, archaeologists and historians say, has broadened understanding of this long overlooked culture, which seemed to have approached the threshold of “civilization” status. Writing had yet to be invented, and so no one knows what the people called themselves. To some scholars, the people and the region are simply Old Europe.

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REALLY? The Claim: Exercise More During the Day, and You Will Sleep Better at Night
By ANAHAD O’CONNOR, The New York Times, December 1, 2009

THE FACTS It has long been said that regular physical activity and better sleep go hand in hand. Burn more energy during the day, the thinking goes, and you will be more tired at night.

But only recently have scientists sought to find out precisely to what extent. One extensive study published this year looked for answers by having healthy children wear actigraphs — devices that measure movement — and then seeing whether more movement and activity during the day meant improved sleep at night. The results should be particularly enlightening to parents.

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We May Be Born With an Urge to Help
By NICHOLAS WADE, The New York Times, December 1, 2009

What is the essence of human nature? Flawed, say many theologians. Vicious and addicted to warfare, wrote Hobbes. Selfish and in need of considerable improvement, think many parents.

But biologists are beginning to form a generally sunnier view of humankind. Their conclusions are derived in part from testing very young children, and partly from comparing human children with those of chimpanzees, hoping that the differences will point to what is distinctively human.

The somewhat surprising answer at which some biologists have arrived is that babies are innately sociable and helpful to others. Of course every animal must to some extent be selfish to survive. But the biologists also see in humans a natural willingness to help.

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