May. 7th, 2013

brdgt: (Science Works by iconomicon)
In Pursuit of an Underwater Menagerie (and related slide show)
By C. DREW HARVELL, The New York Times, May 6, 2013

MAUNA LANI REEF, Hawaii — After a long, cold swim in the dark, we spotted it on the night reef with our dive lights: Octopus ornatus, the ornate octopus, a foot-long creature in an amber shade of orange with bright white spots and dashes along all its arms.

It sat stolidly in the light of the camera, 30 feet below the surface, unfazed by the attention. I reached out a finger and it touched me with its suctioned tentacles. When it scuttled in the other direction, I herded it between my cupped hands as it watched me attentively with searching golden eyes.

As if levitating, it smoothly lifted off and tried to jet over my head, but slowly enough that I could catch it gently in midair — like handling a large bird, albeit one with eight sticky tentacles. Holding it at eye level, I looked into its eyes. I felt connected, sort of an octopus whisperer.

Then a tentacle slapped the front of my mask. The octopus crawled up my arm and vanished into the night.

I’ve been a marine biologist my entire professional life, spending more than 25 years researching the health of corals and sustainability of reefs. I’m captivated by the magic of sessile invertebrates like corals, sponges and sea squirts — creatures vital to the ecosystem yet too often overlooked in favor of more visible animals like sharks and whales.

The filmmaker David O. Brown and I want to change that. To make a documentary, “Fragile Legacy,” we are on a quest to lure these elusive and delicate invertebrates in front of the camera lens.

Our inspiration springs from an unlikely source: a collection of 570 superbly wrought, anatomically perfect glass sculptures of marine creatures from the 19th century.

Read more... )



Psychiatry’s Guide Is Out of Touch With Science, Experts Say
By PAM BELLUCK and BENEDICT CAREY, The New York Times, May 6, 2013

Just weeks before the long-awaited publication of a new edition of the so-called bible of mental disorders, the federal government’s most prominent psychiatric expert has said the book suffers from a scientific “lack of validity.”

The expert, Dr. Thomas R. Insel, director of the National Institute of Mental Health, said in an interview Monday that his goal was to reshape the direction of psychiatric research to focus on biology, genetics and neuroscience so that scientists can define disorders by their causes, rather than their symptoms.

While the Diagnostic and Statistical Manual of Mental Disorders, or D.S.M., is the best tool now available for clinicians treating patients and should not be tossed out, he said, it does not reflect the complexity of many disorders, and its way of categorizing mental illnesses should not guide research.

“As long as the research community takes the D.S.M. to be a bible, we’ll never make progress,” Dr. Insel said, adding, “People think that everything has to match D.S.M. criteria, but you know what? Biology never read that book.”

Read more... )




Jeryl Lynn Hilleman with her sister, Kirsten, in 1966 as a doctor gave her the mumps vaccine developed by their father.



A Forgotten Pioneer of Vaccines
By RICHARD CONNIFF, The New York Times, May 6, 2013

We live in an epidemiological bubble and are for the most part blissfully unaware of it. Diseases that were routine hazards of childhood for many Americans living today now seem like ancient history. And while every mother could once identify measles in a heartbeat, now even the best hospitals have to call in their eldest staff members to ask: “Is this what we think it is?”

To a remarkable extent, we owe our well-being, and in many cases our lives, to the work of one man and to events that happened 50 years ago this spring.

At 1 a.m. on March 21, 1963, an intense, irascible but modest Merck scientist named Maurice R. Hilleman was asleep at his home in the Philadelphia suburb of Lafayette Hill when his 5-year-old daughter, Jeryl Lynn, woke him with a sore throat. Dr. Hilleman felt the side of her face and then the telltale swelling beneath the jaw indicating mumps. He tucked her back into bed, about the only treatment anyone could offer at the time.

For most children, mumps was a nuisance disease, nothing worse than a painful swelling of the salivary glands. But Dr. Hilleman knew that it could sometimes leave a child deaf or otherwise permanently impaired.

He quickly dressed and drove 20 minutes to pick up proper sampling equipment from his laboratory. Returning home, he woke Jeryl Lynn long enough to swab the back of her throat and immerse the specimen in a nutrient broth. Then he drove back to store it in the laboratory freezer.

The name Maurice Hilleman may not ring a bell. But today 95 percent of American children receive the M.M.R. — the vaccine for measles, mumps and rubella that Dr. Hilleman invented, starting with the mumps strain he collected that night from his daughter.

Read more... )

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